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CSF1R Antibody

CAT: 0247-OAAN01017-200ULSize: 200 µLDry Ice: NoHazardous: No
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CAT#:0247-OAAN01017-200ULSize:200 µL
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CAS Number
9007-83-4
Gene Name
Colony stimulating factor 1 receptor
Gene Aliases
FMS, CSFR, FIM2, HDLS, C-FMS, CD115, CSF-1R, BANDDOS, M-CSF-R
Gene ID
1436
Swiss Prot
P07333
Accession Number
NP_001275634.1
Reactivity
Human
Immunogen
A synthetic peptide of human CSF1R
Target
The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. Expression of a splice variant from an LTR promoter has been found in Hodgkin lymphoma (HL), HL cell lines and anaplastic large cell lymphoma.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid.// PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Reconstitution
Store at -20° C. Avoid repeated freeze/thaw cycles._x005F
Molecular Weight
108 kDa
Fragment
IgG
NCBI Gene Symbol
CSF1R
Host or Source
Rabbit
Protein Name
Macrophage colony-stimulating factor 1 receptor
Gene Name URL
CSF1R
Nucleotide Accession Number
NM_001288705.1

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