MCAM Antibody

• Gene Name :

  Melanoma cell adhesion molecule

• Gene Aliases :

  CD146; cell surface glycoprotein MUC18; cell surface glycoprotein P1H12; Gicerin; HEMCAM; melanoma adhesion molecule; Melanoma cell adhesion molecule; melanoma-associated antigen A32; melanoma-associated antigen MUC18; MelCAM; METCAM; MUC18; S-endo 1 endothelial-associated antigen.

• Gene ID :

  4162

• Swiss Prot :

  P43121

• Accession Number :

  NP_006491.2

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  CD146/MCAM

• Target :

  Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  Western blot

• Purification :

  Affinity purified against immunogen

• Assay Protocol :

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Format :

  Liquid

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Reconstitution :

  Store at -20C. Avoid repeated freeze/thaw cycles.

• Molecular Weight :

  72kDa

• Fragment :

  IgG

• NCBI Gene Symbol :

  MCAM

• Host or Source :

  Rabbit

• Protein Name :

  Cell surface glycoprotein MUC18

• Gene Name URL :

  MCAM

• CAS Number :

  9007-83-4

• Nucleotide Accession Number :

  NM_006500.2