PDE4D Antibody

• Gene Name :

  Phosphodiesterase 4D

• Gene Aliases :

  DPDE3, PDE43, STRK1, ACRDYS2, HSPDE4D, PDE4DN2

• Gene ID :

  5144

• Swiss Prot :

  Q08499

• Accession Number :

  NP_001098101.1

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant protein of human PDE4D

• Target :

  PDE4D (cAMP-specific 3',5'-cyclic phosphodiesterase 4D) is also named as DPDE3, PDE43 and belongs to the cyclic nucleotide phosphodiesterase family and PDE4 subfamily. PDE4D subtype may be of particular importance as an antidepressant target in that it is regulated by repeated treatment with both norepinephrine and serotonin reuptake inhibitors as well as by the PDE4 inhibitor rolipram (PMID:16730340) . It has at least 9 isoforms and all 9 PDE4D isoforms are expressed in healthy adult human hippocampus and in hippocampus from a patient with advanced Alzheimer disease (PMID:17353396) . This antibody is specific to PDE4D.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB, IHC, IF

• Purification :

  Affinity purification.

• Assay Protocol :

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Format :

  Liquid.// PBS with 0.02% sodium azide, 50% glycerol, pH 7.3

• Reconstitution :

  Store at -20C. Avoid repeated freeze/thaw cycles.

• Molecular Weight :

  91 kDa

• Fragment :

  IgG

• NCBI Gene Symbol :

  PDE4D

• Host or Source :

  Rabbit

• Protein Name :

  CAMP-specific 3',5'-cyclic phosphodiesterase 4D

• Gene Name URL :

  PDE4D

• CAS Number :

  9007-83-4

• Nucleotide Accession Number :

  NM_001104631.1