Products for Research Use Only
RegisterLogin

ROCK1 Antibody

CAT: 0247-OAAN00166-200ULSize: 200 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OAAN00166-200ULSize:200 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9007-83-4
Gene Name
Rho associated coiled-coil containing protein kinase 1
Gene Aliases
ROCK-I, P160ROCK
Gene ID
6093
Swiss Prot
Q13464
Accession Number
NP_005397.1
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human ROCK1
Target
This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. A pseudogene, related to this gene, is also located on chromosome 18.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC
Purification
Affinity purified against immunogen
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Reconstitution
Store at -20C. Avoid repeated freeze/thaw cycles.
Molecular Weight
158 kDa
Fragment
IgG
NCBI Gene Symbol
ROCK1
Host or Source
Rabbit
Protein Name
Rho-associated protein kinase 1
Gene Name URL
ROCK1
Nucleotide Accession Number
NM_005406.2

Related Products

CatalogName
OPCD06734-50UGROCK1 Recombinant Protein
OPCD06734-200UGROCK1 Recombinant Protein
OPCD06734-10UGROCK1 Recombinant Protein
OKEH06554-96WROCK1 ELISA Kit (Human)
AAP97435-100UGROCK1 Peptide - middle region (AAP97435)
OCOA12629-20UGOCOA12629-20UG - ROCK1 Protein Lysate
OKEH06554ROCK1 ELISA Kit (Human) (OKEH06554)
OKWB00390ROCK1 ELISA Kit (Rat) (OKWB00390)
OKCA00999ROCK1 ELISA Kit (Rat) (OKCA00999)
OABB01870-100UGROCK2 Antibody

Alternative Products

CatalogName
10R-8041ROCK1 antibody

Popular Products