NOTCH2 Antibody

CAT: 0247-OAAN00109-100ULSize: 100 µLDry Ice: NoHazardous: No
CAT#:0247-OAAN00109-100ULSize:100 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
CAS Number
9007-83-4
Gene Name
Notch 2
Gene Aliases
HN2, AGS2, HJCYS
Gene ID
4853
Swiss Prot
Q04721
Accession Number
NP_001186930.1
Reactivity
Human, Mouse
Immunogen
Recombinant protein of human NOTCH2
Target
This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. Two transcript variants encoding different isoforms have been found for this gene.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC
Purification
Affinity purified against immunogen
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Reconstitution
Store at -20C. Avoid repeated freeze/thaw cycles.
Molecular Weight
265 kDa
Fragment
IgG
NCBI Gene Symbol
NOTCH2
Host or Source
Rabbit
Protein Name
Neurogenic locus notch homolog protein 2
Gene Name URL
NOTCH2
Nucleotide Accession Number
NM_001200001.1

Related Products

CatalogName
OPCD05745-10UGNOTCH2 Recombinant Protein
OPCD05745-200UGNOTCH2 Recombinant Protein
OPCD05745-50UGNOTCH2 Recombinant Protein
OKEH03506-96WNOTCH2 ELISA Kit (Rat)
OKEH05163-96WNOTCH2 ELISA Kit (Mouse)
OKEH01647-96WNOTCH2 ELISA Kit (Human)
OKCD09281-96WNOTCH2 ELISA Kit (Human)
AAP32723-100UGNOTCH2 Peptide - middle region (AAP32723)
OKEH03506NOTCH2 ELISA Kit (Rat) (OKEH03506)
OKEH05163NOTCH2 ELISA Kit (Mouse) (OKEH05163)

Alternative Products

CatalogName
MBS8580869-01NOTCH2 Antibody

Popular Products