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FBXW12 Antibody

CAT: 0247-OAAL00978-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OAAL00978-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
F-box and WD repeat domain containing 12
Gene Aliases
F-box and WD-40 domain protein 12; F-box and WD-40 domain-containing protein 12; F-box- and WD40-repeat-containing protein; F-box only protein 35; F-box/WD repeat-containing protein 12; FBW12; FBXO12; FBXO35.
Gene ID
285231
Accession Number
https://www.ncbi.nlm.nih.gov/protein/NP_996985.1
Reactivity
Human, Mouse
Immunogen
FBXW12 (NP_996985.1, 265 a.a. ~ 354 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Target
Members of the F-box protein family, such as FBXW12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]) .[supplied by OMIM
Clonality
Monoclonal
Clone
1A9
Type
Monoclonal Antibody
Sequence
LLRPSEGSDPLSTFLPHKLCASACWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYM
Applications
Enzyme-linked immunosorbent assay|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
Fragment
IgG2a Kappa
NCBI Gene Symbol
FBXW12
Host or Source
Mouse
Protein Name
F-box/WD repeat-containing protein 12 isoform 1 [Homo sapiens]|Homo sapiens F-box and WD repeat domain containing 12 (FBXW12), transcript variant 1, mRNA
Gene Name URL
FBXW12
Nucleotide Accession Number
https://www.ncbi.nlm.nih.gov/nuccore/NM_207102

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