SECISBP2 Antibody

CAT: 0247-OAAL00805-100UGSize: 100 µgDry Ice: NoHazardous: No
CAT#:0247-OAAL00805-100UGSize:100 µg
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AVAILABILITY: InStock
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CAS Number
9007-83-4
Gene Name
SECIS binding protein 2
Gene Aliases
SBP2; Sec insertion sequence-binding protein 2; selenocysteine insertion sequence-binding protein 2.
Gene ID
79048
Accession Number
https://www.ncbi.nlm.nih.gov/protein/NP_076982.3
Reactivity
Human, Mouse
Immunogen
SECISBP2 (NP_076982.3, 106 a.a. ~ 205 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Target
The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. The gene described in this record encodes a nuclear protein that functions as a SECIS binding protein. Mutations in this gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism. [provided by RefSeq
Clonality
Monoclonal
Clone
3A7
Type
Monoclonal Antibody
Sequence
VPGSQYLYNQPSCYRGFQTVKHRNENTCPLPQEMKALFKKKTYDEKKTYDQQKFDSERADGTISSEIKSARGSHHLSIYAENSLKSDGYHKRTDRKSRII
Applications
Enzyme-linked immunosorbent assay|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
Fragment
IgG2a Kappa
NCBI Gene Symbol
SECISBP2
Host or Source
Mouse
Protein Name
Homo sapiens SECIS binding protein 2 (SECISBP2), transcript variant 1, mRNA|selenocysteine insertion sequence-binding protein 2 isoform 1 [Homo sapiens]
Gene Name URL
SECISBP2
Nucleotide Accession Number
https://www.ncbi.nlm.nih.gov/nuccore/NM_024077

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