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NUMB Antibody

CAT: 0247-OAAL00407-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OAAL00407-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
NUMB endocytic adaptor protein
Gene Aliases
C14_5527; C14orf41; h-Numb; numb homolog; protein numb homolog; S171.
Gene ID
8650
Accession Number
https://www.ncbi.nlm.nih.gov/protein/AAH33824
Reactivity
Human, Mouse
Immunogen
NUMB (AAH33824, 1 a.a. ~ 135 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Target
The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Clonality
Monoclonal
Clone
4A7-A6
Type
Monoclonal Antibody
Sequence
MPYPAPNVPVVGITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASADRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL
Applications
Enzyme-linked immunosorbent assay|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
Fragment
IgG1 kappa
NCBI Gene Symbol
NUMB
Host or Source
Mouse
Protein Name
Homo sapiens numb homolog (Drosophila), mRNA (cDNA clone IMAGE:5217787), complete cds|NUMB protein [Homo sapiens]
Gene Name URL
NUMB
Nucleotide Accession Number
https://www.ncbi.nlm.nih.gov/nuccore/BC033824

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