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TCAP Antibody

CAT: 0247-OAAL00404-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OAAL00404-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Titin-cap
Gene Aliases
19 kDa sarcomeric protein; CMD1N; CMH25; LGMD2G; LGMDR7; limb girdle muscular dystrophy 2G (autosomal recessive) ; T-cap; TELE; telethonin; teneurin C-terminal associated peptide; titin cap protein.
Gene ID
8557
Accession Number
https://www.ncbi.nlm.nih.gov/protein/AAH12628
Reactivity
Human, Mouse
Immunogen
TCAP (AAH12628, 1 a.a. ~ 167 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Target
Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. [provided by RefSeq
Clonality
Monoclonal
Clone
2B1
Type
Monoclonal Antibody
Sequence
MATSELSCEVSEENCERREAFWAEWKDLTLSTRPEEGCSLHEEDTQRHETYHQQGQCQVLVQRSPWLMMRMGILGRGLQEYQLPYQRVLPLPIFTPAKMGATKEEREDTPIQLQELLALETALGGQCVDRQEVAEITKQLPPVVPVSKPGALRRSLSRSMSQEAQRG
Applications
Enzyme-linked immunosorbent assay
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
Fragment
IgG1 kappa
NCBI Gene Symbol
TCAP
Host or Source
Mouse
Protein Name
Homo sapiens titin-cap (telethonin), mRNA (cDNA clone MGC:13679 IMAGE:4251080), complete cds|Titin-cap (telethonin) [Homo sapiens]
Gene Name URL
TCAP
Nucleotide Accession Number
https://www.ncbi.nlm.nih.gov/nuccore/BC012628

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