CDC14A Antibody

CAT: 0247-OAAL00403-100UGSize: 100 µgDry Ice: NoHazardous: No
CAT#:0247-OAAL00403-100UGSize:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Cell division cycle 14A
Gene Aliases
CDC10 (cell division cycle 10, S. cerevisiae, homolog) ; cdc14; CDC14 cell division cycle 14 homolog A; DFNB105; DFNB32; DFNB35; dual specificity protein phosphatase CDC14A; hCDC14.
Gene ID
8556
Accession Number
https://www.ncbi.nlm.nih.gov/protein/NP_003663
Reactivity
Human, Mouse
Immunogen
CDC14A (NP_003663, 431 a.a. ~ 530 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Target
The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of this gene results in several transcript variants encoding distinct isoforms. [provided by RefSeq
Clonality
Monoclonal
Clone
2C12
Type
Monoclonal Antibody
Sequence
PFRLSSSLQGSAVTLKTSKMALSPSATAKRINRTSLSSGATVRSFSINSRLASSLGNLNAATDDPENKKTSSSSKAGFTASPFTNLLNGSSQPTTRNYPE
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
Fragment
IgG2b Kappa
NCBI Gene Symbol
CDC14A
Host or Source
Mouse
Protein Name
Dual specificity protein phosphatase CDC14A isoform 1 [Homo sapiens]|Homo sapiens cell division cycle 14A (CDC14A), transcript variant 1, mRNA
Gene Name URL
CDC14A
Nucleotide Accession Number
https://www.ncbi.nlm.nih.gov/nuccore/NM_003672

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