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TAP1 Antibody

CAT: 0247-OAAL00325-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OAAL00325-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Transporter 1, ATP binding cassette subfamily B member
Gene Aliases
ABC transporter, MHC 1; ABC17; ABCB2; antigen peptide transporter 1; APT1; ATP-binding cassette sub-family B member 2; ATP-binding cassette, sub-family B (MDR/TAP), member 2; D6S114E; peptide supply factor 1; peptide transporter involved in antigen processing 1; peptide transporter PSF1; peptide transporter TAP1; PSF1; PSF-1; really interesting new gene 4 protein; RING4; TAP1*0102N; TAP1N; transporter 1 ATP-binding cassette sub-family B; transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) ; transporter associated with antigen processing; transporter, ATP-binding cassette, major histocompatibility complex, 1.
Gene ID
6890
Accession Number
https://www.ncbi.nlm.nih.gov/protein/AAH14081
Reactivity
Human, Mouse
Immunogen
TAP1 (AAH14081, 241 a.a. ~ 350 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Target
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. [provided by RefSeq
Clonality
Monoclonal
Clone
1B11
Type
Monoclonal Antibody
Sequence
GSETRRLSLFLVLVVLSSLGEMAIPFFTGRLTDWILQDGSADTFTRNLTLMSILTIASAVLEFVGDGIYNNTMGHVHSHLQGEVFGAVLRQETEFFQQNQTGNIMSRVTE
Applications
Enzyme-linked immunosorbent assay|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
Fragment
IgG3 Kappa
NCBI Gene Symbol
TAP1
Host or Source
Mouse
Protein Name
Homo sapiens transporter 1, ATP-binding cassette, sub-family B (MDR/TAP), mRNA (cDNA clone MGC:20334 IMAGE:4304716), complete cds|Transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) [Homo sapiens]
Gene Name URL
TAP1
Nucleotide Accession Number
https://www.ncbi.nlm.nih.gov/nuccore/BC014081

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