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PAFAH1B1 Antibody

CAT: 0247-OAAL00231-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OAAL00231-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Platelet activating factor acetylhydrolase 1b regulatory subunit 1
Gene Aliases
LIS1; LIS2; lissencephaly 1 protein; MDCR; MDS; NudF; PAFAH; platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) ; platelet-activating factor acetylhydrolase IB subunit beta.
Gene ID
5048
Accession Number
https://www.ncbi.nlm.nih.gov/protein/NP_000421
Reactivity
Human, Mouse
Immunogen
PAFAH1B1 (NP_000421, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Target
This locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller-Dieker lissencephaly syndrome. This gene encodes the non-catalytic alpha subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase, a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine) . Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist: one composed of multiple subunits, the other, a single subunit. In addition, a single-subunit isoform of this enzyme is found in serum. [provided by RefSeq
Clonality
Monoclonal
Clone
5A5
Type
Monoclonal Antibody
Sequence
MVLSQRQRDELNRAIADYLRSNGYEEAYSVFKKEAELDVNEELDKKYAGLLEKKWTSVIRLQKKVMELESKLNEAKEEFTSGGPLGQKRDPKEWIPRPPEKYALSGHRSP
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
Fragment
IgG2a Kappa
NCBI Gene Symbol
PAFAH1B1
Host or Source
Mouse
Protein Name
Homo sapiens platelet activating factor acetylhydrolase 1b regulatory subunit 1 (PAFAH1B1), mRNA|platelet-activating factor acetylhydrolase IB subunit alpha [Homo sapiens]
Gene Name URL
PAFAH1B1
Nucleotide Accession Number
https://www.ncbi.nlm.nih.gov/nuccore/NM_000430

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