GJB2 Antibody

CAT: 0247-OAAL00120-100UGSize: 100 µgDry Ice: NoHazardous: No
CAT#:0247-OAAL00120-100UGSize:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Gap junction protein beta 2
Gene Aliases
BAPS; connexin 26; CX26; DFNA3; DFNA3A; DFNB1; DFNB1A; gap junction beta 2 proteinc; gap junction beta-2 protein; gap junction protein, beta 2, 26kDa; HID; KID; mutant gap junction beta 2 protein; mutant gap junction protein beta 2; NSRD1; PPK.
Gene ID
2706
Accession Number
https://www.ncbi.nlm.nih.gov/protein/AAH17048
Reactivity
Human, Mouse
Immunogen
GJB2 (AAH17048, 1 a.a. ~ 226 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Target
This gene encodes a member of the gap junction protein family. The gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells. The gap junction proteins, also known as connexins, purified from fractions of enriched gap junctions from different tissues differ. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene are responsible for as much as 50% of pre-lingual, recessive deafness. [provided by RefSeq
Clonality
Monoclonal
Clone
1C6
Type
Monoclonal Antibody
Sequence
MDWGTLQTILGGVNKHSTSIGKIWLTVLFIFRIMILVVAAKEVWGDEQADFVCNTLQPGCKNVCYDHYFPISHIRLWALQLIFVSTPALLVAMHVAYRRHEKKRKFIKGEIKSEFKDIEEIKTQKVRIEGSLWWTYTSSIFFRVIFEAAFMYVFYVMYDGFSMQRLVKCNAWPCPNTVDCFVSRPTEKTVFTVFMIAVSGICILLNVTELCYLLIRYCSGKSKKPV
Applications
Enzyme-linked immunosorbent assay|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
Fragment
IgG2b Kappa
NCBI Gene Symbol
GJB2
Host or Source
Mouse
Protein Name
Gap junction protein, beta 2, 26kDa [Homo sapiens]|Homo sapiens gap junction protein, beta 2, 26kDa, mRNA (cDNA clone MGC:9238 IMAGE:3850394), complete cds
Gene Name URL
GJB2
Nucleotide Accession Number
https://www.ncbi.nlm.nih.gov/nuccore/BC017048

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