Products for Research Use Only
RegisterLogin

ETF1 Antibody

CAT: 0247-OAAL00094-100UGSize: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OAAL00094-100UGSize:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9007-83-4
Gene Name
Eukaryotic translation termination factor 1
Gene Aliases
D5S1995; ERF; ERF1; eukaryotic peptide chain release factor subunit 1; polypeptide chain release factor 1; protein Cl1; RF1; sup45 (yeast omnipotent suppressor 45) homolog-like 1; SUP45L1; TB3-1.
Gene ID
2107
Accession Number
https://www.ncbi.nlm.nih.gov/protein/NP_004721.1
Reactivity
Human, Mouse
Immunogen
ETF1 (NP_004721.1, 338 a.a. ~ 437 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Target
Termination of protein biosynthesis and release of the nascent polypeptide chain are signaled by the presence of an in-frame stop codon at the aminoacyl site of the ribosome. The process of translation termination is universal and is mediated by protein release factors (RFs) and GTP. A class 1 RF recognizes the stop codon and promotes the hydrolysis of the ester bond linking the polypeptide chain with the peptidyl site tRNA, a reaction catalyzed at the peptidyl transferase center of the ribosome. Class 2 RFs, which are not codon specific and do not recognize codons, stimulate class 1 RF activity and confer GTP dependency upon the process. In prokaryotes, both class 1 RFs, RF1 and RF2, recognize UAA; however, UAG and UGA are decoded specifically by RF1 and RF2, respectively. In eukaryotes, eRF1, or ETF1, the functional counterpart of RF1 and RF2, functions as an omnipotent RF, decoding all 3 stop codons (Frolova et al., 1994 [PubMed 7990965]) .[supplied by OMIM
Clonality
Monoclonal
Clone
2H4
Type
Monoclonal Antibody
Sequence
TEEEKILYLTPEQEKDKSHFTDKETGQEHELIESMPLLEWFANNYKKFGATLEIVTDKSQEGSQFVKGFGGIGGILRYRVDFQGMEYQGGDDEFFDLDDY
Applications
Enzyme-linked immunosorbent assay|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
Fragment
IgG2b Kappa
NCBI Gene Symbol
ETF1
Host or Source
Mouse
Protein Name
Eukaryotic peptide chain release factor subunit 1 isoform 1 [Homo sapiens]|Homo sapiens eukaryotic translation termination factor 1 (ETF1), transcript variant 1, mRNA
Gene Name URL
ETF1
Nucleotide Accession Number
https://www.ncbi.nlm.nih.gov/nuccore/NM_004730

Related Products

CatalogName
OCOA01362-20UGETF1 Protein Lysate
OKEH03707-96WETF1 ELISA Kit (Rat)
OKEH02953-96WETF1 ELISA Kit (Human)
OKEH03673-96WETF1 ELISA Kit (Mouse)
OKEH03707ETF1 ELISA Kit (Rat) (OKEH03707)
OKEH03673ETF1 ELISA Kit (Mouse) (OKEH03673)
OKEH02953ETF1 ELISA Kit (Human) (OKEH02953)
AAP54738-100UGETF1 Peptide - N-terminal region (AAP54738)
OAGA04639-100ULETFA Antibody
OAAN02359-50ULETFA Antibody

Alternative Products

CatalogName
70R-17155ETF1 antibody

Popular Products