DSC2 Antibody

CAT: 0247-OAAL00080-100UGSize: 100 µgDry Ice: NoHazardous: No
CAT#:0247-OAAL00080-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Desmocollin 2
Gene Aliases
ARVD11; cadherin family member 2; CDHF2; desmocollin-2; desmosomal glycoprotein II/III; DG2; DGII/III; DSC3.
Gene ID
1824
Accession Number
https://www.ncbi.nlm.nih.gov/protein/NP_077740.1
Reactivity
Human, Mouse
Immunogen
DSC2 (NP_077740.1, 444 a.a. ~ 534 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Target
The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11. Alternative splicing results in two transcript variants encoding distinct isoforms. [provided by RefSeq
Clonality
Monoclonal
Clone
1F2
Type
Monoclonal Antibody
Sequence
SREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKENAEVGTTSNGYKAYDPETRSSSGIRYKKLTDPTGWVTIDENTGSIKVFRSLD
Applications
Enzyme-linked immunosorbent assay|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
Fragment
IgG2b Kappa
NCBI Gene Symbol
DSC2
Host or Source
Mouse
Protein Name
Desmocollin-2 isoform Dsc2a preproprotein [Homo sapiens]|Homo sapiens desmocollin 2 (DSC2), transcript variant Dsc2a, mRNA
Gene Name URL
DSC2
Nucleotide Accession Number
https://www.ncbi.nlm.nih.gov/nuccore/NM_024422

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