GRB2 Antibody

• CAS Number :

  9007-83-4

• Gene Aliases :

  ASH, Grb3-3, MST084, NCKAP2, MSTP084, EGFRBP-GRB2

• Gene ID :

  2885

• Swiss Prot :

  P62993

• Accession Number :

  NP_002077

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant protein of human GRB2, corresponding to a region within C-terminal amino acids.

• Target :

  Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Isoform 2 does not bind to phosphorylated epidermal growth factor receptor (EGFR) but inhibits EGF-induced transactivation of a RAS-responsive element. Isoform 2 acts as a dominant negative protein over GRB2 and by suppressing proliferative signals, may trigger active programmed cell death.

• Clonality :

  Polyclonal

• Type :

  Polyclonal Antibody

• Applications :

  WB, IHC

• Purification :

  Peptide affinity chromatography

• Assay Protocol :

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration :

  1 mg/mL

• Format :

  Liquid// PBS (pH 7.4), 150mM NaCl, 0.02% sodium azide and 50% glycerol

• Reconstitution :

  Store at -20° C. Stable for 12 months from date of receipt.

• Molecular Weight :

  25 kDa

• Fragment :

  IgG

• NCBI Gene Symbol :

  GRB2

• Host or Source :

  Rabbit

• Protein Name :

  Growth factor receptor-bound protein 2

• Gene Name URL :

  GRB2

• Nucleotide Accession Number :

  NM_002086