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FBP1 Antibody

CAT: 0247-OAAJ07791-100ULSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0247-OAAJ07791-100ULSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Aliases
FBP
Gene ID
2203
Swiss Prot
P09467
Accession Number
NP_000498
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human FBP1
Target
Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
WB, IHC
Purification
Immunogen affinity chromatography
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/mL
Format
Liquid
Reconstitution
Store at +4C. For long term storage, aliquot and store at -20C. Avoid freeze/thaw cycles.
Molecular Weight
37 kDa
NCBI Gene Symbol
FBP1
Host or Source
Rabbit
Protein Name
Fructose-1,6-bisphosphatase 1
Gene Name URL
FBP1
Nucleotide Accession Number
NM_000507

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