CD46 Antibody

• Gene Aliases :

  MCP, TLX, AHUS2, MIC10, TRA2.10

• Gene ID :

  4179

• Swiss Prot :

  P15529

• Accession Number :

  NP_002380

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant proteinof human CD46

• Target :

  Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity.

• Clonality :

  Polyclonal

• Type :

  Polyclonal Antibody

• Applications :

  WB, IHC

• Purification :

  Immunogen affinity chromatography

• Assay Protocol :

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration :

  1 mg/mL

• Format :

  Liquid

• Reconstitution :

  Store at +4C. For long term storage, aliquot and store at -20C. Avoid freeze/thaw cycles.

• Molecular Weight :

  43 kDa

• NCBI Gene Symbol :

  CD46

• Host or Source :

  Rabbit

• Protein Name :

  Membrane cofactor protein

• Gene Name URL :

  CD46

• CAS Number :

  9007-83-4

• Nucleotide Accession Number :

  NM_002389