Products for Research Use Only
RegisterLogin

BIRC5 Antibody

CAT: 0247-OAAJ06926-100ULSize: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OAAJ06926-100ULSize:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9007-83-4
Gene Aliases
API4, EPR-1
Gene ID
332
Swiss Prot
O15392
Accession Number
NP_001012270
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant Protein of human BIRC5
Target
Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis. Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with polymerized microtubules. The complex with RAN plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. May counteract a default induction of apoptosis in G2/M phase. The acetylated form represses STAT3 transactivation of target gene promoters. May play a role in neoplasia. Inhibitor of CASP3 and CASP7. Isoform 2 and isoform 3 do not appear to play vital roles in mitosis. Isoform 3 shows a marked reduction in its anti-apoptotic effects when compared with the displayed wild-type isoform.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
WB, IHC
Purification
Immunogen affinity chromatography
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/mL
Format
Liquid
Reconstitution
Store at +4C. For long term storage, aliquot and store at -20C. Avoid freeze/thaw cycles.
Molecular Weight
16 kDa
NCBI Gene Symbol
BIRC5
Host or Source
Rabbit
Protein Name
Baculoviral IAP repeat-containing protein 5
Gene Name URL
BIRC5
Nucleotide Accession Number
NM_001012270

Related Products

CatalogName
OAOA21486-100UGBIRC5 Capture Antibody
OAOA21487-100UGBIRC5 Capture Antibody
OAOA21949-50UGBIRC5 Detection Antibody
OAOA21948-50UGBIRC5 Detection Antibody
OPCD07253-10UGBIRC5 Recombinant Protein
OPCA01486-20UGBirc5 Recombinant Protein
OCOA00415-20UGBIRC5 Protein Lysate
OCOA16594-20UGBIRC5 Protein Lysate
OPCA02604-100UGBirc5 Recombinant Protein
OPCD07254-200UGBIRC5 Recombinant Protein

Alternative Products

CatalogName
10R-3454BIRC5 antibody

Popular Products