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RAB11A Antibody

CAT: 0247-OAAJ06775-100ULSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0247-OAAJ06775-100ULSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Aliases
YL8
Gene ID
8766
Swiss Prot
P62491
Accession Number
NP_001193765
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human RAB11A.
Target
Rab11a, Rab11b and Rab25 are members of the Rab11 family of small Ras-like GTPases. Rab11 (isoforms Rab11a and Rab11b) functions as a key regulator in the recycling of perinuclear, plasma membrane and Golgi compartment endosomes. Despite some overlap, distinct differences exist between Rab11a and Rab11b in both their cellular distribution and functional roles. Rab11a is ubiquitously expressed while Rab11b is found mainly in the heart and brain. Like other Rab proteins, Rab11 exerts its function via interactions with Rab11 family interacting proteins (FIPs) . While there are three distinct classes of FIPs, all appear to share a conserved carboxy-terminal Rabbinding domain that allows Rab-FIP protein interaction. When bound together, these proteins are thought to regulate membrane-associated protein sorting.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
WB, IHC
Purification
The antiserum was purified by peptide affinity chromatography.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/mL
Format
Liquid.// PBS pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Reconstitution
Store at -20C. Stable for 12 months from date of receipt._x005F
Molecular Weight
24 kDa
Fragment
IgG
Specificity
RAB11A Ab detects endogenous levels of total RAB11A.
NCBI Gene Symbol
RAB11A
Host or Source
Rabbit
Protein Name
Ras-related protein Rab-11A
Gene Name URL
RAB11A
Nucleotide Accession Number
NM_001206836

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