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JUP Antibody

CAT: 0247-OAAJ06621-100ULSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0247-OAAJ06621-100ULSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Aliases
PG, DP3, PDGB, PKGB, CTNNG, DPIII
Gene ID
3728
Swiss Prot
P14923
Accession Number
NP_002221
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant proteinof human JUP
Target
Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton .
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
WB, IHC
Purification
Immunogen affinity chromatography
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/mL
Format
Liquid
Reconstitution
Store at +4C. For long term storage, aliquot and store at -20C. Avoid freeze/thaw cycles.
Molecular Weight
82 kDa
NCBI Gene Symbol
JUP
Host or Source
Rabbit
Protein Name
Junction plakoglobin
Gene Name URL
JUP
Nucleotide Accession Number
NM_002230

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