RegisterLogin

KRT17 Antibody

CAT: 0247-OAAJ06458-100ULSize: 100 µLDry Ice: NoHazardous: No
CAT#:0247-OAAJ06458-100ULSize:100 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
CAS Number
9007-83-4
Gene Aliases
PC, K17, PC2, 39.1, CK-17, PCHC1
Gene ID
3872
Swiss Prot
Q04695
Accession Number
NP_000413
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human Keratin 17
Target
Type I keratin involved in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair . Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state . Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway . Involved in tissue repair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial "stem cells". Acts as a promoter of epithelial proliferation by acting a regulator of immune response in skin: promotes Th1/Th17-dominated immune environment contributing to the development of basaloid skin tumors . May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
WB, IHC, IF
Purification
Immunogen affinity chromatography
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/mL
Format
Liquid
Reconstitution
Store at +4C. For long term storage, aliquot and store at -20C. Avoid freeze/thaw cycles.
Molecular Weight
48 kDa
NCBI Gene Symbol
KRT17
Host or Source
Rabbit
Protein Name
Keratin, type I cytoskeletal 17
Gene Name URL
KRT17
Nucleotide Accession Number
NM_000422

Related Products

CatalogName
OPCD04743-50UGKRT17 Recombinant Protein
OPCD04743-10UGKRT17 Recombinant Protein
OPCA01684-1MGKRT17 Recombinant Protein
OPCD04743-200UGKRT17 Recombinant Protein
OPCD04744-50UGKRT17 Recombinant Protein
OPCD04744-10UGKRT17 Recombinant Protein
OPCA01684-20UGKRT17 Recombinant Protein
AAP41733-100UGKRT17 Peptide (AAP41733)
OPCD04744-200UGKRT17 Recombinant Protein
OPCA01684-100UGKRT17 Recombinant Protein

Alternative Products

CatalogName
MBS8516368-01KRT17 Antibody

Popular Products