TFEB Antibody

CAT: 0247-OAAJ04002-100ULSize: 100 µLDry Ice: NoHazardous: No
CAT#:0247-OAAJ04002-100ULSize:100 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
CAS Number
9007-83-4
Gene Aliases
TCFEB, BHLHE35, ALPHATFEB
Gene ID
7942
Swiss Prot
P19484
Accession Number
NP_001161299
Reactivity
Human, Mouse
Immunogen
A synthesized peptide
Target
Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3') . Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4+ T-cells and thymus-dependent humoral immunity. Specifically recognizes and binds the CLEAR-box sequence (5'-GTCACGTGAC-3') present in the regulatory region of many lysosomal genes, leading to activate their expression. It thereby plays a central role in expression of lysosomal genes. Acts as a positive regulator of autophagy by promoting expression of genes involved in autophagy. Specifically recognizes the gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobulin enhancer. Plays a role in the signal transduction processes required for normal vascularization of the placenta.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
WB, IHC
Purification
Immunogen affinity chromatography
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/mL
Format
Liquid
Reconstitution
Store at +4C. For long term storage, aliquot and store at -20C. Avoid freeze/thaw cycles.
Molecular Weight
52 kDa
NCBI Gene Symbol
TFEB
Host or Source
Rabbit
Protein Name
Transcription factor EB
Gene Name URL
TFEB
Nucleotide Accession Number
NM_001167827

Related Products

CatalogName
AAP38810-100UGTFEB Peptide (AAP38810)
OCOA11778-20UGTFEB Protein Lysate
AAP58116-100UGTFEB Peptide - middle region (AAP58116)
AAP72647-100UGTFEB Peptide - C-terminal region (AAP72647)
OAAJ04003-100ULTFE3 Antibody
OAAL00578-100UGTFEC Antibody
OAEB01034-100UGTFE3 Antibody
OAAJ01960-100ULTFE3 Antibody
OAEB01693-100UGTFEC Antibody
OAAF02179-100UGTFE3 Antibody

Alternative Products

CatalogName
MBS8513851-01TFEB Antibody

Popular Products