GRK6 Antibody

• Gene Aliases:

  GPRK6

• Gene ID:

  2870

• Swiss Prot:

  P43250

• Accession Number:

  NP_001004105

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthesized peptide

• Target:

  Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis . Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro) .

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Applications:

  WB, IF, ICC

• Purification:

  Immunogen affinity chromatography

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1 mg/mL

• Format:

  Liquid

• Reconstitution:

  Store at +4C. For long term storage, aliquot and store at -20C. Avoid freeze/thaw cycles.

• Molecular Weight:

  65 kDa

• NCBI Gene Symbol:

  GRK6

• Host or Source:

  Rabbit

• Protein Name:

  G protein-coupled receptor kinase 6

• Gene Name URL:

  GRK6

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_001004105