CHEK2 Antibody (Phospho-Thr387)

• Gene Name:

  Checkpoint kinase 2

• Gene Aliases:

  CDS1, CHK2, LFS2, RAD53, hCds1, HuCds1, PP1425

• Gene ID:

  11200

• Swiss Prot:

  O96017

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthesized peptide derived from human Chk2 around the phosphorylation site of Threonine 387

• Target:

  In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. The protein encoded by this gene is a cell cycle checkpoint regulator and putative tumor suppressor.

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC

• Purification:

  Immunogen affinity purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1 mg/ml

• Format:

  Liquid. Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Reconstitution:

  Store at -20C. Stable for 12 months from date of receipt.

• Molecular Weight:

  62 kDa

• Specificity:

  Phospho-Chk2 (Thr387) antibody detects endogenous levels of Chk2 only when phosphorylated at Threonine 387

• NCBI Gene Symbol:

  CHEK2

• Host or Source:

  Rabbit

• Gene Name URL:

  CHEK2

• CAS Number:

  9007-83-4