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KSR2 Antibody

CAT: 0247-OAAJ02176-100ULSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0247-OAAJ02176-100ULSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Kinase suppressor of ras 2
Gene Aliases
FLJ25965, hKSR2, Kinase suppressor of Ras 2, kinase suppressor of Ras-2, KSR2
Gene ID
283455
Swiss Prot
Q6VAB6
Reactivity
Human, Mouse
Immunogen
A synthesized peptide derived from human KSR2
Target
KSR2 Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Interacts with MAP2K1, MAP3K8, MAPK, RAS and RAF. 2 isoforms of the human protein are produced by alternative splicing.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
WB, IF, ICC
Purification
Immunogen affinity purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Liquid. Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Reconstitution
Store at -20C. Stable for 12 months from date of receipt.
Molecular Weight
108 kDa
Specificity
KSR2 antibody detects endogenous levels of KSR2
NCBI Gene Symbol
KSR2
Host or Source
Rabbit
Gene Name URL
KSR2

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