STEAP3 Antibody

• Gene Name :

  STEAP family member 3, metalloreductase

• Gene Aliases :

  STMP3, TSAP6, pHyde, AHMIO2, dudlin-2, dudulin-2

• Gene ID :

  55240

• Swiss Prot :

  Q658P3

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  A synthesized peptide derived from human STEA3

• Target :

  STEAP3 a multi-pass membrane protein induced directly by p53. Plays an important role in facilitating exosome secretion. Enhances secretion in the DNA damage-induced p53-dependent exosomal secretory pathway. Localizes to vesicular-like structures at the plasma membrane and around the nucleus. Highly expressed in hematopoietic tissues where it localizes to the specialized endosome. An endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe (3+) to Fe (2+) . Can also reduce of Cu (2+) to Cu (1+), suggesting that it participates in copper homeostasis. Uses NAD (+) as acceptor.

• Clonality :

  Polyclonal

• Type :

  Polyclonal Antibody

• Applications :

  WB, IF, ICC

• Purification :

  Immunogen affinity purified

• Assay Protocol :

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration :

  1 mg/ml

• Format :

  Liquid. Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Reconstitution :

  Store at -20C. Stable for 12 months from date of receipt.

• Molecular Weight :

  54 kDa

• Specificity :

  STEA3 antibody detects endogenous levels of STEA3

• NCBI Gene Symbol :

  STEAP3

• Host or Source :

  Rabbit

• Gene Name URL :

  STEAP3

• CAS Number :

  9007-83-4