MAP4K4 Antibody

CAT: 0247-OAAJ02051-100ULSize: 100 µLDry Ice: NoHazardous: No
CAT#:0247-OAAJ02051-100ULSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Mitogen-activated protein kinase kinase kinase kinase 4
Gene Aliases
HGK, NIK, MEKKK4, FLH21957, HEL-S-31
Gene ID
9448
Swiss Prot
O95819
Reactivity
Human, Mouse
Immunogen
A synthesized peptide derived from human MEKKK 4
Target
A Ser/Thr kinase of the STE20 subfamily. May play a role in the response to environmental stress and cytokines such as TNF-alpha. May interact with the SH3 domain of the adapter proteins Nck. Binds, via its CNH regulatory domain, to the N- terminal region of SPG3A. Upregulated in primary tumors and tumor cell lines. Required for anchorage-independent growth and ras-dependent focus formation in multiple cell lines. 5 isoforms of the human protein are produced by alternative splicing.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
WB, IF, ICC
Purification
Immunogen affinity purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Liquid. Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Reconstitution
Store at -20C. Stable for 12 months from date of receipt.
Molecular Weight
142 kDa
Specificity
MEKKK 4 antibody detects endogenous levels of MEKKK 4
NCBI Gene Symbol
MAP4K4
Host or Source
Rabbit
Gene Name URL
MAP4K4

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