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FGFR3 Antibody

CAT: 0247-OAAJ01759-100ULSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0247-OAAJ01759-100ULSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Fibroblast growth factor receptor 3
Gene Aliases
ACH, CEK2, JTK4, CD333, HSFGFR3EX
Gene ID
2261
Swiss Prot
P22607
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human FGFR3, corresponding to a region within C-terminal amino acids
Target
FGFR3 a receptor tyrosine kinase of the highly-conserved FGFR family that binds fibroblast growth factor (FGF) . Mutations are associated with thanatophoric dysplasia (TD), craniosynostosis Adelaide type, many craniosynostotic syndromes and bone malformations. Three splice-variant isoforms have been described. Activating point mutations cause dwarfism, including achondroplasia, hypochrondroplasia and thanatophoric dysplasia, and facial and other morphogenetic disorders, including Crouzon syndrome, craniosynostosis Adelaide type, San Diego skeletal displasia and Muenke syndrome. Translocations t (4;14) involving the IgH region are common in multiple myeloma and frequently involve FGFR3.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
WB, IHC, ICF, IF
Purification
Purified by peptide affinity chromatography
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Liquid// PBS (pH 7.4) 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Reconstitution
Store at -20° C. Stable for 12 months from date of receipt.
Molecular Weight
95 kDa
Specificity
FGFR3 antibody detects endogenous levels of total FGFR3
NCBI Gene Symbol
FGFR3
Host or Source
Rabbit
Gene Name URL
FGFR3

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