CASP3 Antibody

• Gene Name :

  Caspase-3

• Gene Aliases :

  CPP32, SCA-1, CPP32B

• Gene ID :

  836

• Swiss Prot :

  P42574

• Accession Number :

  NP_004337.2NP_116786.1

• Reactivity :

  Human

• Immunogen :

  This Aviva monoclonal antibody is produced by immunizing mice with recombinant polypeptide (Aviva SEAL mAb technology) corresponding to surface multi-epitopes of human Caspase-3.

• Target :

  This gene is a member of the cysteine-aspartic acid protease (caspase) family. Alternative splicing of this gene results in two transcript variants that encode the same protein. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases-3 exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Caspases-3 cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10

• Clonality :

  Monoclonal

• Type :

  Monoclonal Antibody

• Source :

  Mouse mAb

• Applications :

  WB, IF, IHC

• Assay Protocol :

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Reconstitution :

  Store the product at -20C. Stable for one year from the date of shipment.

• Molecular Weight :

  32 kDa

• Fragment :

  Mouse IgG

• Specificity :

  Caspase-3 Mouse monoclonal antibody detects endogenous levels of Caspase-3 protein.

• Protein Length :

  277

• NCBI Gene Symbol :

  CASP3

• Host or Source :

  Mouse

• Protein Name :

  Caspase-3

• Gene Name URL :

  CASP3

• CAS Number :

  9007-83-4

• Nucleotide Accession Number :

  NM_004346.3NM_032991.2