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CASP3 Antibody

CAT: 0247-OAAH00031-100ULSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0247-OAAH00031-100ULSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Caspase-3
Gene Aliases
CPP32, SCA-1, CPP32B
Gene ID
836
Swiss Prot
P42574
Accession Number
NP_004337.2NP_116786.1
Reactivity
Human
Immunogen
This Aviva monoclonal antibody is produced by immunizing mice with recombinant polypeptide (Aviva SEAL mAb technology) corresponding to surface multi-epitopes of human Caspase-3.
Target
This gene is a member of the cysteine-aspartic acid protease (caspase) family. Alternative splicing of this gene results in two transcript variants that encode the same protein. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases-3 exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Caspases-3 cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10
Clonality
Monoclonal
Type
Monoclonal Antibody
Source
Mouse mAb
Applications
WB, IF, IHC
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Reconstitution
Store the product at -20C. Stable for one year from the date of shipment.
Molecular Weight
32 kDa
Fragment
Mouse IgG
Specificity
Caspase-3 Mouse monoclonal antibody detects endogenous levels of Caspase-3 protein.
Protein Length
277
NCBI Gene Symbol
CASP3
Host or Source
Mouse
Protein Name
Caspase-3
Gene Name URL
CASP3
Nucleotide Accession Number
NM_004346.3NM_032991.2

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