STAT3 Antibody

• Gene Name:

  Signal transducer and activator of transcription 3

• Gene Aliases:

  APRF, HIES, ADMIO, ADMIO1

• Gene ID:

  6774

• Swiss Prot:

  P40763

• Accession Number:

  NP_003141.2NP_644805.1NP_998827.1XP_005257673.2XP_005257674.2

• Reactivity:

  Human, Mouse, Rat, Chinese hamster, Dog

• Immunogen:

  This Aviva monoclonal antibody is produced by immunizing mice with a recombinant polypeptide (Aviva SEAL mAb technology) corresponding to urface multi-epitopes of human Stat3.

• Target:

  The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. Stat3 is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis.

• Clonality:

  Monoclonal

• Type:

  Monoclonal Antibody

• Source:

  Mouse mAb

• Applications:

  WB

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Reconstitution:

  Store the product at -20C. Stable for one year from the date of shipment.

• Molecular Weight:

  88 kDa

• Fragment:

  Mouse IgG

• Specificity:

  Stat3 monoclonal antibody detects endogenous levels of Stat3 protein.

• Protein Length:

  770

• NCBI Gene Symbol:

  STAT3

• Host or Source:

  Mouse

• Protein Name:

  Signal transducer and activator of transcription 3

• Gene Name URL:

  STAT3

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_003150.3NM_139276.2NM_213662.1XM_005257616.2XM_005257617.2