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S100B Antibody

CAT: 0247-OAAF08347-100ULSize: 100 µLDry Ice: NoHazardous: No
CAT#:0247-OAAF08347-100ULSize:100 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
S100 calcium binding protein B
Gene Aliases
NEF, S100, S100-B, S100beta
Gene ID
6285
Swiss Prot
P04271
Accession Number
NP_006263.1
Immunogen
The antiserum was produced against synthesized peptide derived between 10-50 aa of human S100B. The exact sequence is proprietary.
Target
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.
Clonality
Monoclonal
Clone
ABT-S100B
Type
Monoclonal Antibody
Applications
IHC-P
Purification
Immunogen affinity purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid. Supplied in 1% BSA, 0.05M Tris-HCl, 0.15M NaCl, 0.2% Kathon CG/ICP, 0.1% Tween-20
Reconstitution
Shipped at 4C. Store at -20C. Stable for 12 months at -20C.
Molecular Weight
11 kDa
Fragment
IgG
Specificity
Anti-S100 [ABT-S100B] detects endogenous levels of total S100 protein.
NCBI Gene Symbol
S100B
Host or Source
Mouse
Protein Name
Protein S100-B
Gene Name URL
S100B
Nucleotide Accession Number
XM_017028424.1

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