S100B Antibody

• Gene Name:

  S100 calcium binding protein B

• Gene Aliases:

  NEF, S100, S100-B, S100beta

• Gene ID:

  6285

• Swiss Prot:

  P04271

• Accession Number:

  NP_006263.1

• Immunogen:

  The antiserum was produced against synthesized peptide derived between 10-50 aa of human S100B. The exact sequence is proprietary.

• Target:

  The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.

• Clonality:

  Monoclonal

• Clone:

  ABT-S100B

• Type:

  Monoclonal Antibody

• Applications:

  IHC-P

• Purification:

  Immunogen affinity purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Format:

  Liquid. Supplied in 1% BSA, 0.05M Tris-HCl, 0.15M NaCl, 0.2% Kathon CG/ICP, 0.1% Tween-20

• Reconstitution:

  Shipped at 4C. Store at -20C. Stable for 12 months at -20C.

• Molecular Weight:

  11 kDa

• Fragment:

  IgG

• Specificity:

  Anti-S100 [ABT-S100B] detects endogenous levels of total S100 protein.

• NCBI Gene Symbol:

  S100B

• Host or Source:

  Mouse

• Protein Name:

  Protein S100-B

• Gene Name URL:

  S100B

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  XM_017028424.1