PIK3CA Antibody

• Gene Name:

  Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

• Gene Aliases:

  MCM, CWS5, MCAP, PI3K, CLAPO, CLOVE, MCMTC, PI3K-alpha, p110-alpha

• Gene ID:

  5290

• Swiss Prot:

  P42336

• Accession Number:

  NP_006209.2

• Immunogen:

  The antiserum was produced against synthesized peptide derived between 1010-1068 aa of human PIK3CA. The exact sequence is proprietary.

• Target:

  Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns (4,5) P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. A pseudogene of this gene has been defined on chromosome 22.

• Clonality:

  Monoclonal

• Clone:

  ABT-PI3.H1047R

• Type:

  Monoclonal Antibody

• Applications:

  WB, IHC-P

• Purification:

  Immunogen affinity purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Format:

  Liquid. Supplied in 1% BSA, 0.05M Tris-HCl, 0.15M NaCl, 0.2% Kathon CG/ICP, 0.1% Tween-20

• Reconstitution:

  Shipped at 4C. Store at -20C. Stable for 12 months at -20C.

• Molecular Weight:

  124 kDa

• Fragment:

  IgG

• Specificity:

  Anti-PIK3CA H1047R [ABT-PI3.H1047R] detects endogenous levels of total PIK3CA H1047R protein.

• NCBI Gene Symbol:

  PIK3CA

• Host or Source:

  Mouse

• Protein Name:

  Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

• Gene Name URL:

  PIK3CA

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  XM_011512894.2