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MBP Antibody

CAT: 0247-OAAF08324-100ULSize: 0.1 mLDry Ice: NoHazardous: No
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CAT#:0247-OAAF08324-100ULSize:0.1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Myelin basic protein
Gene Aliases
Golli-MBP; myelin A1 protein; myelin basic protein; myelin membrane encephalitogenic protein; proline-rich proteoglycan 2.
Gene ID
4155
Swiss Prot
P02686
Accession Number
NP_001020252.1
Reactivity
Human
Immunogen
Synthetic peptide
Target
The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.
Clonality
Monoclonal
Clone
ABT-MBP
Type
Monoclonal Antibody
Applications
Immunohistochemistry
Purification
Immunogen affinity purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
PBS, pH7.2, 0.03% Proclin 300, 50% glycerol
Reconstitution
-20°C
Molecular Weight
33 kDa
Fragment
IgG
Specificity
Anti-Myelin Basic Protein (MBP) [ABT-MBP] detects endogenous levels of total Myelin Basic Protein (MBP) protein.
NCBI Gene Symbol
MBP
Host or Source
Mouse
Protein Name
Myelin basic protein
Gene Name URL
MBP
Nucleotide Accession Number
NM_001025081.1

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