CDH16 Antibody

• Gene Name:

  Cadherin 16

• Gene Aliases:

  Cadherin-16, Kidney-specific cadherin, Ksp-cadherin, CDH16

• Gene ID:

  1014

• Swiss Prot:

  O75309

• Accession Number:

  NP_001191673.1

• Immunogen:

  The antiserum was produced against synthesized peptide derived between 60-100 aa of human CDH16. The exact sequence is proprietary.

• Target:

  This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified.

• Clonality:

  Monoclonal

• Clone:

  ABT-CDH16

• Type:

  Monoclonal Antibody

• Applications:

  IHC-P

• Purification:

  Immunogen affinity purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Format:

  Liquid. Supplied in 1% BSA, 0.05M Tris-HCl, 0.15M NaCl, 0.2% Kathon CG/ICP, 0.1% Tween-20

• Reconstitution:

  Shipped at 4C. Store at -20C. Stable for 12 months at -20C.

• Molecular Weight:

  90 kDa

• Fragment:

  IgG

• Specificity:

  Anti-KSP-Cadherin [ABT-CDH16] detects endogenous levels of total KSP-Cadherin protein.

• NCBI Gene Symbol:

  CDH16

• Host or Source:

  Mouse

• Protein Name:

  Cadherin-16

• Gene Name URL:

  CDH16

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_001204744.1