PTPRC Antibody

CAT: 0247-OAAF08264-50ULSize: 0.05 mLDry Ice: NoHazardous: No
CAT#:0247-OAAF08264-50ULSize:0.05 mL
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CAS Number
9007-83-4
Gene Name
Protein tyrosine phosphatase receptor type C
Gene Aliases
B220; CD45; CD45 antigen; CD45R; GP180; LCA; L-CA; Leukocyte common antigen; LY5; protein tyrosine phosphatase, receptor type, c polypeptide; receptor-type tyrosine-protein phosphatase C; T200; T200 glycoprotein; T200 leukocyte common antigen.
Gene ID
5788
Swiss Prot
P08575
Accession Number
NP_002829.3
Reactivity
Human
Immunogen
Synthetic peptide.
Target
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity) .
Clonality
Monoclonal
Clone
ABT-CD45
Type
Monoclonal Antibody
Applications
Immunohistochemistry
Purification
Immunogen affinity purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
PBS, pH7.2, 0.03% Proclin 300, 50% glycerol
Reconstitution
-20°C
Molecular Weight
131 kDa
Fragment
IgG
Specificity
Anti-CD45 (LCA) [ABT-CD45] detects endogenous levels of total CD45 (LCA) protein.
NCBI Gene Symbol
PTPRC
Host or Source
Mouse
Protein Name
Receptor-type tyrosine-protein phosphatase C
Gene Name URL
PTPRC
Nucleotide Accession Number
NM_002838.4

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