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PTGDR2 Antibody

CAT: 0247-OAAF08137-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OAAF08137-100UGSize:100 µg
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Description
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CAS Number
9007-83-4
Gene Name
Prostaglandin D2 receptor 2
Gene Aliases
CD294; chemoattractant receptor homologous molecule expressed on T helper type 2 cells; chemoattractant receptor-homologous molecule expressed on TH2 cells; CRTH2; DL1R; DP2; GPR44; G-protein coupled receptor 44; prostaglandin D2 receptor 2; putative G-protein coupled receptor 44.
Gene ID
11251
Swiss Prot
Q9Y5Y4
Reactivity
Human|Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human PTGDR2.
Target
Receptor for prostaglandin D2 (PGD2) . Coupled to the G (i) -protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca (2+) mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses.
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
LNTVPYFVFRDTISRLDGRIMCYYNVLLLNPGPDRDATCNSRQVALAVSK
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using peptide.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1mg/ml
Reconstitution
-20°C
Molecular Weight
43 kDa
Specificity
PTGDR2 Antibody detects endogenous levels of PTGDR2 protein.
NCBI Gene Symbol
PTGDR2
Host or Source
Rabbit
Protein Name
Prostaglandin D2 receptor 2
Gene Name URL
PTGDR2

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