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WNT1 Antibody

CAT: 0247-OAAF07897-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OAAF07897-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Wnt family member 1
Gene Aliases
BMND16; INT1; OI15; proto-oncogene Int-1 homolog; proto-oncogene Wnt-1; wingless-type MMTV integration site family member 1; wingless-type MMTV integration site family, member 1 (oncogene INT1) .
Gene ID
7471
Swiss Prot
P04628
Reactivity
Human|Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human WNT1.
Target
Ligand for members of the frizzled family of seven transmembrane receptors (Probable) . Acts in the canonical Wnt signaling pathway by promoting beta-catenin-dependent transcriptional activation (PubMed:23499309, PubMed:26902720, PubMed:28528193, PubMed:23656646) . In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling (By similarity) . Plays an essential role in the development of the embryonic brain and central nervous system (CNS) (By similarity) . Has a role in osteoblast function, bone development and bone homeostasis (PubMed:23499309, PubMed:23656646) .
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
YSGRLGTAGTAGRACNSSSPALDGCELLCCGRGHRTRTQRVTERCNCTFH
Applications
Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1mg/ml
Reconstitution
-20°C
Molecular Weight
40 kDa
Notes
Formerly GWB-ASD254
Specificity
WNT1 Antibody detects endogenous levels of total WNT1 protein.
NCBI Gene Symbol
WNT1
Host or Source
Rabbit
Protein Name
Proto-oncogene Wnt-1
Gene Name URL
WNT1

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