CD57 Antibody

• Gene Name:

  Beta-1,3-glucuronyltransferase 1

• Gene Aliases:

  Beta-1,3-glucuronyltransferase 1; CD57; galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1; GLCATP; GLCUATP; glucuronosyltransferase P; HNK1; LEU7; LEU7 antigen; NK1; NK-1; UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase.

• Gene ID:

  27087

• Swiss Prot:

  Q9P2W7

• Reactivity:

  Human|Mouse|Rat

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human CD57.

• Target:

  Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group.

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Applications:

  Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin

• Purification:

  The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1 mg/ml

• Reconstitution:

  -20°C

• Molecular Weight:

  38 kDa

• Specificity:

  CD57 antibody detects endogenous levels of CD57.

• NCBI Gene Symbol:

  B3GAT1

• Host or Source:

  Rabbit

• Protein Name:

  Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

• Gene Name URL:

  B3GAT1

• CAS Number:

  9007-83-4