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GPR143 Antibody

CAT: 0247-OAAF04919-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OAAF04919-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
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CAS Number
9007-83-4
Gene Name
G protein-coupled receptor 143
Gene Aliases
G-protein coupled receptor 143; NYS6; OA1; ocular albinism 1; ocular albinism type 1 protein.
Gene ID
4935
Swiss Prot
P51810
Accession Number
NP_000264.2
Reactivity
Human|Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human GPR143.
Target
Receptor for tyrosine, L-DOPA and dopamine. After binding to L-DOPA, stimulates Ca (2+) influx into the cytoplasm, increases secretion of the neurotrophic factor SERPINF1 and relocalizes beta arrestin at the plasma membrane; this ligand-dependent signaling occurs through a G (q) -mediated pathway in melanocytic cells. Its activity is mediated by G proteins which activate the phosphoinositide signaling pathway. Plays also a role as an intracellular G protein-coupled receptor involved in melanosome biogenesis, organization and transport.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Dilution
The optimal working dilution should be determined by the end user.
Format
Liquid
Reconstitution
-20°C
Molecular Weight
43 kDa
Notes
Formerly GWB-ASF316
Specificity
GPR143 antibody detects endogenous levels of total GPR143 protein.
NCBI Gene Symbol
GPR143
Host or Source
Rabbit
Protein Name
G-protein coupled receptor 143
Gene Name URL
GPR143

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