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BAI1 Antibody

CAT: 0247-OAAF04857-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OAAF04857-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Adhesion G protein-coupled receptor B1
Gene Aliases
Adhesion G protein-coupled receptor B1; BAI1; brain-specific angiogenesis inhibitor 1; GDAIF.
Gene ID
575
Swiss Prot
O14514
Accession Number
NP_001693.2
Reactivity
Human|Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human BAI1.
Target
Phosphatidylserine receptor which enhances the engulfment of apoptotic cells (PubMed:24509909) . Also mediates the binding and engulfment of Gram-negative bacteria (PubMed:26838550) . Stimulates production of reactive oxygen species by macrophages in response to Gram-negative bacteria, resulting in enhanced microbicidal macrophage activity (PubMed:26838550) . In the gastric mucosa, required for recognition and engulfment of apoptotic gastric epithelial cells (PubMed:24509909) . Promotes myoblast fusion (By similarity) . Activates the Rho pathway in a G-protein-dependent manner (PubMed:23782696) . Inhibits MDM2-mediated ubiquitination and degradation of DLG4/PSD95, promoting DLG4 stability and regulating synaptic plasticity (By similarity) . Required for the formation of dendritic spines by ensuring the correct localization of PARD3 and TIAM1 (By similarity) . Potent inhibitor of angiogenesis in brain and may play a significant role as a mediator of the p53/TP53 signal in suppression of glioblastoma (PubMed:11875720) .
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Dilution
The optimal working dilution should be determined by the end user.
Format
Liquid
Reconstitution
-20°C
Molecular Weight
173 kDa
Notes
Formerly GWB-ASF258
Specificity
BAI1 antibody detects endogenous levels of total BAI1 protein.
NCBI Gene Symbol
ADGRB1
Host or Source
Rabbit
Protein Name
Adhesion G protein-coupled receptor B1
Gene Name URL
ADGRB1

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