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SLC4A8 Antibody

CAT: 0247-OAAF04323-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OAAF04323-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Solute carrier family 4 member 10|solute carrier family 4 member 8
Gene Aliases
Electroneutral Na (+) -driven Cl-HCO3 exchanger; electroneutral sodium bicarbonate exchanger 1; k-NBC3; NBC3; NBCn2; NCBE; NDCBE; sodium-driven chloride bicarbonate exchanger; Solute carrier family 4 member 10; Solute carrier family 4 member 8; solute carrier family 4, sodium bicarbonate cotransporter, member 8; solute carrier family 4, sodium bicarbonate cotransporter-like, member 10; solute carrier family 4, sodium bicarbonate transporter, member 10.
Gene ID
57282|9498
Swiss Prot
Q2Y0W8|Q6U841
Accession Number
NP_001035049.1
Reactivity
Human|Mouse|Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human SLC4A8/10.
Target
Electrogenic sodium/bicarbonate cotransporter in exchange for intracellular chloride. Plays an important role in regulating intracellular pH (By similarity) .|Mediates electroneutral sodium- and carbonate-dependent chloride-HCO3 (-) exchange with a Na (+) :HCO3 (-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3 (-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3 (-) into the cells. Also mediates lithium-dependent HCO3 (-) cotransport. May be regulated by osmolarity.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Dilution
The optimal working dilution should be determined by the end user.
Format
Liquid
Reconstitution
-20°C
Molecular Weight
125 kDa
Notes
Formerly GWB-ASF031
Specificity
SLC4A8/10 antibody detects endogenous levels of total SLC4A8/10 protein.
NCBI Gene Symbol
SLC4A10|SLC4A8
Host or Source
Rabbit
Protein Name
Electroneutral sodium bicarbonate exchanger 1|Sodium-driven chloride bicarbonate exchanger
Gene Name URL
SLC4A10|SLC4A8

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