Products for Research Use Only
RegisterLogin

PPP4R2 Antibody

CAT: 0247-OAAF04268-100UGSize: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OAAF04268-100UGSize:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9007-83-4
Gene Name
Protein phosphatase 4 regulatory subunit 2
Gene Aliases
PP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2.
Gene ID
151987
Swiss Prot
Q9NY27
Accession Number
NP_777567.1
Reactivity
Human|Monkey
Immunogen
The antiserum was produced against synthesized peptide derived from human PPP4R2.
Target
Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4) . May regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair. Mediates RPA2 dephosphorylation by recruiting PPP4C to RPA2 in a DNA damage-dependent manner. RPA2 dephosphorylation is required for the efficient RPA2-mediated recruitment of RAD51 to chromatin following double strand breaks, an essential step for DNA repair.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Dilution
The optimal working dilution should be determined by the end user.
Format
Liquid
Reconstitution
-20°C
Molecular Weight
46 kDa
Notes
Formerly GWB-ASF000
Specificity
PP4R2 antibody detects endogenous levels of total PP4R2 protein.
NCBI Gene Symbol
PPP4R2
Host or Source
Rabbit
Protein Name
Serine/threonine-protein phosphatase 4 regulatory subunit 2
Gene Name URL
PPP4R2

Related Products

CatalogName
AAP42719-100UGPPP4R2 Peptide - C-terminal region (AAP42719)
OAAN02702-50ULPPP6R2 Antibody
OAGA04989-100ULPPP4R1 Antibody
OAAN02310-200ULPPP3R2 Antibody
OACA08472-100ULPPP3R2 Antibody
OAAN02702-200ULPPP6R2 Antibody
OAAN02704-50ULPPP4R1 Antibody
OAAN02704-100ULPPP4R1 Antibody
OAAN02704-200ULPPP4R1 Antibody
OAAF01154-100UGPPP1R2 Antibody

Alternative Products

CatalogName
70R-3940PPP4R2 antibody

Popular Products