Products for Research Use Only
RegisterLogin

RIOK3 Antibody

CAT: 0247-OAAF04253-100UGSize: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OAAF04253-100UGSize:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9007-83-4
Gene Name
RIO kinase 3
Gene Aliases
Homolog of the Aspergillus nidulans sudD gene product; RIO kinase 3; serine/threonine-protein kinase RIO3; SUDD; sudD (suppressor of bimD6, Aspergillus nidulans) homolog; sudD homolog; sudD suppressor of Aspergillus nidulans bimD6 homolog; sudD suppressor of bimD6 homolog; testicular secretory protein Li 47.
Gene ID
8780
Swiss Prot
O14730
Accession Number
NP_003822.2
Reactivity
Human|Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human RIOK3.
Target
Involved in regulation of type I interferon (IFN) -dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses. May act as an adapter protein essential for the recruitment of TBK1 to IRF3 (PubMed:24807708) . Phosphorylates IFIH1 on 'Ser-828' interfering with IFIH1 filament assembly on long dsRNA and resulting in attenuated IFIH1-signaling (PubMed:25865883) . Can inhibit CASP10 isoform 7-mediated activation of the NF-kappaB signaling pathway (PubMed:19557502) . May play a role in the biogenesis of the 40S ribosomal subunit. Involved in the processing of 21S pre-rRNA to the mature 18S rRNA (PubMed:22418843) .
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Western blot
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Dilution
The optimal working dilution should be determined by the end user.
Format
Liquid
Reconstitution
-20°C
Molecular Weight
59 kDa
Notes
Formerly GWB-ASE989
Specificity
RIOK3 antibody detects endogenous levels of total RIOK3 protein.
NCBI Gene Symbol
RIOK3
Host or Source
Rabbit
Protein Name
Serine/threonine-protein kinase RIO3
Gene Name URL
RIOK3

Related Products

CatalogName
AAP42152-100UGRIOK3 Peptide (AAP42152)
OCOA05960-20UGRIOK3 Protein Lysate
OKEH05202-96WRIOK3 ELISA Kit (Human)
OKEH05201-96WRIOK3 ELISA Kit (Mouse)
OKEH05202RIOK3 ELISA Kit (Human) (OKEH05202)
OKEH05201RIOK3 ELISA Kit (Mouse) (OKEH05201)
ARP57210_P050-25ULRIOK2 Antibody - middle region
ARP60622_P050-25ULRIOK1 Antibody - C-terminal region
ARP57210_P050RIOK2 antibody - middle region (ARP57210_P050)
ARP57209_P050-25ULRIOK2 Antibody - N-terminal region

Alternative Products

CatalogName
70R-19903RIOK3 antibody

Popular Products