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STK36 Antibody

CAT: 0247-OAAF04241-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OAAF04241-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Serine/threonine kinase 36
Gene Aliases
CILD46; FU; fused homolog; serine/threonine-protein kinase 36; testicular tissue protein Li 188.
Gene ID
27148
Swiss Prot
Q9NRP7
Accession Number
NP_001230242.1
Reactivity
Human|Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human STK36.
Target
Serine/threonine protein kinase which plays an important role in the sonic hedgehog (Shh) pathway by regulating the activity of GLI transcription factors (PubMed:10806483) . Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization (PubMed:10806483) . GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur (PubMed:10806483) . Required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function (By similarity) . Essential for construction of the central pair apparatus of motile cilia.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Dilution
The optimal working dilution should be determined by the end user.
Format
Liquid
Reconstitution
-20°C
Molecular Weight
143 kDa
Notes
Formerly GWB-ASE979
Specificity
STK36 antibody detects endogenous levels of total STK36 protein.
NCBI Gene Symbol
STK36
Host or Source
Rabbit
Protein Name
Serine/threonine-protein kinase 36
Gene Name URL
STK36

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