Products for Research Use Only
RegisterLogin

IFITM3 Antibody

CAT: 0247-OAAF02990-100UGSize: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OAAF02990-100UGSize:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9007-83-4
Gene Name
Interferon induced transmembrane protein 3
Gene Aliases
1-8U; dispanin subfamily A member 2b; DSPA2b; interferon-induced transmembrane protein 3; interferon-inducible protein 1-8U; IP15.
Gene ID
10410
Swiss Prot
Q01628
Accession Number
NP_066362.2
Reactivity
Human|Mouse|Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human IFM3.
Target
IFN-induced antiviral protein which disrupts intracellular cholesterol homeostasis. Inhibits the entry of viruses to the host cell cytoplasm by preventing viral fusion with cholesterol depleted endosomes. May inactivate new enveloped viruses which buds out of the infected cell, by letting them go out with a cholesterol depleted membrane. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV) and Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV) . Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Plays a critical role in the structural stability and function of vacuolar ATPase (v-ATPase) . Establishes physical contact with the v-ATPase of endosomes which is critical for proper clathrin localization and is also required for the function of the v-ATPase to lower the pH in phagocytic endosomes thus establishing an antiviral state.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Western blot
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Dilution
The optimal working dilution should be determined by the end user.
Format
Liquid
Reconstitution
-20°C
Molecular Weight
14 kDa
Notes
Formerly GWB-ASE155
Specificity
IFM3 antibody detects endogenous levels of total IFM3 protein.
NCBI Gene Symbol
IFITM3
Host or Source
Rabbit
Protein Name
Interferon-induced transmembrane protein 3
Gene Name URL
IFITM3

Related Products

CatalogName
OCOA08919-20UGIFITM3 Protein Lysate
OKEH02042-96WIFITM3 ELISA Kit (Human)
AAP84349-100UGIFITM3 Peptide - N-terminal region (AAP84349)
OKCD05591-96WIFITM3 Chemi-Luminescent ELISA Kit (Human)
OKEH02042IFITM3 ELISA Kit (Human) : 96 Wells (OKEH02042)
OKCD05591IFITM3 Chemi-Luminescent ELISA Kit (Human) (OKCD05591)
OACA09400-50UGIFITM5 Antibody
OAGA01686-100ULIFITM1 Antibody
OACA03134-100UGIFITM2 Antibody
OACA03134-50UGIFITM2 Antibody

Alternative Products

CatalogName
70R-50796IFITM3 antibody

Popular Products