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GAB4 Antibody

CAT: 0247-OAAF02976-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OAAF02976-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
GRB2 associated binding protein 2|GRB2 associated binding protein family member 4
Gene Aliases
Grb2-associated binder 2; GRB2-associated binder 2-like; GRB2-associated binder 2-like protein; GRB2-associated binder 4; GRB2-associated-binding protein 2; GRB2-associated-binding protein 2-like; GRB2-associated-binding protein 4; growth factor receptor bound protein 2-associated protein 2; growth factor receptor bound protein 2-associated protein 4; pp100.
Gene ID
128954|9846
Swiss Prot
Q2WGN9|Q9UQC2
Accession Number
NP_001032903.1
Reactivity
Human|Mouse|Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human GAB2.
Target
Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Dilution
The optimal working dilution should be determined by the end user.
Format
Liquid
Reconstitution
-20°C
Molecular Weight
62 kDa
Specificity
GAB4 antibody detects endogenous levels of total GAB4 protein.
NCBI Gene Symbol
GAB2|GAB4
Host or Source
Rabbit
Protein Name
GRB2-associated-binding protein 2|GRB2-associated-binding protein 4
Gene Name URL
GAB2|GAB4

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