MRC2 Antibody

• CAS Number :

  9007-83-4

• Gene Name :

  Mannose receptor C type 2

• Gene Aliases :

  CD280; CLEC13E; C-type lectin domain family 13 member E; C-type mannose receptor 2; ENDO180; endocytic receptor (macrophage mannose receptor family) ; endocytic receptor 180; macrophage mannose receptor 2; UPARAP; UPAR-associated protein; urokinase-type plasminogen activator receptor-associated protein.

• Gene ID :

  9902

• Swiss Prot :

  Q9UBG0

• Accession Number :

  NP_006030.2

• Reactivity :

  Human|Mouse|Rat

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human MRC2.

• Target :

  May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs) .

• Clonality :

  Polyclonal

• Type :

  Polyclonal Antibody

• Applications :

  Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot

• Purification :

  The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

• Assay Protocol :

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration :

  1 mg/ml

• Format :

  Liquid.// PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

• Reconstitution :

  -20°C

• Molecular Weight :

  166 kDa

• Notes :

  Formerly GWB-ASD918

• Fragment :

  IgG

• Specificity :

  MRC2 antibody detects endogenous levels of total MRC2 protein.

• NCBI Gene Symbol :

  MRC2

• Host or Source :

  Rabbit

• Protein Name :

  C-type mannose receptor 2

• Gene Name URL :

  MRC2