STEAP3 Antibody

• Description :

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• Gene Name :

  STEAP3 metalloreductase

• Gene Aliases :

  AHMIO2; dudlin-2; dudulin-2; metalloreductase STEAP3; pHyde; six-transmembrane epithelial antigen of prostate 3; STEAP family member 3, metalloreductase; STMP3; TSAP6; tumor suppressor pHyde; tumor suppressor-activated pathway protein 6.

• Gene ID :

  55240

• Swiss Prot :

  Q658P3

• Accession Number :

  NP_001008410.1

• Reactivity :

  Human|Mouse|Rat

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human STEA3.

• Target :

  Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe (3+) to Fe (2+) . Can also reduce of Cu (2+) to Cu (1+), suggesting that it participates in copper homeostasis. Uses NADP (+) as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.

• Clonality :

  Polyclonal

• Type :

  Polyclonal Antibody

• Applications :

  Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot

• Purification :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Assay Protocol :

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Dilution :

  The optimal working dilution should be determined by the end user.

• Format :

  Liquid

• Reconstitution :

  -20°C

• Molecular Weight :

  54 kDa

• Notes :

  Formerly GWB-ASD723

• Specificity :

  STEA3 antibody detects endogenous levels of total STEA3 protein.

• NCBI Gene Symbol :

  STEAP3

• Host or Source :

  Rabbit

• Protein Name :

  Metalloreductase STEAP3

• Gene Name URL :

  STEAP3

• CAS Number :

  9007-83-4