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MAP3K9 Antibody

CAT: 0247-OAAF02346-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OAAF02346-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
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CAS Number
9007-83-4
Gene Name
Mitogen-activated protein kinase kinase kinase 9
Gene Aliases
MEKK9; mitogen-activated protein kinase kinase kinase 9; Mixed lineage kinase 1; mixed lineage kinase 1 (tyr and ser/thr specificity) ; MLK1; PRKE1.
Gene ID
4293
Swiss Prot
P80192
Accession Number
NP_149132.2
Reactivity
Human|Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human MAP3K9.
Target
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade through the phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7 which in turn activate the JNKs. The MKK/JNK signaling pathway regulates stress response via activator protein-1 (JUN) and GATA4 transcription factors. Plays also a role in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Dilution
The optimal working dilution should be determined by the end user.
Format
Liquid
Reconstitution
-20°C
Molecular Weight
121 kDa
Notes
Formerly GWB-ASD587
Specificity
MAP3K9 antibody detects endogenous levels of total MAP3K9 protein.
NCBI Gene Symbol
MAP3K9
Host or Source
Rabbit
Protein Name
Mitogen-activated protein kinase kinase kinase 9
Gene Name URL
MAP3K9

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